Os01g0580100

Top 300 coexpressed genes (in field leaf samples)

MR Cor OsID description
1.0 1.00 Os01g0580100 Alg9-like mannosyltransferase family protein.
6.0 0.77 Os06g0621500 Disease resistance protein family protein.
8.1 0.81 Os03g0825700 Similar to Defective in exine formation.
9.6 0.75 Os10g0327300 Similar to Phosphatidate cytidylyltransferase (EC 2.7.7.41).
10.4 0.79 Os02g0477700 Similar to Type II inositol-1,4,5-trisphosphate 5-phosphatase 12 (EC 3.1.3.36) (At5PTase12) (FRAGILE FIBER3 protein).
11.0 0.78 Os07g0477500 Conserved hypothetical protein.
12.3 0.76 Os08g0451000 Sec34-like protein family protein.
14.9 0.80 Os05g0437500 Yip1 domain containing protein.
16.9 0.70 Os11g0149100 Protein of unknown function DUF296 domain containing protein.
16.9 0.76 Os01g0724500 Similar to ABC transporter (PDR5-like) isolog (PDR1 ABC transporter).
19.4 0.79 Os12g0104800 Similar to Clathrin heavy chain.
23.5 0.79 Os03g0784800 Cell differentiation proteins, Rcd1-like family protein.
26.1 0.76 Os01g0265000 Geranylgeranyl reductase family protein.
28.2 0.79 Os03g0836000 Similar to Actin 7 (Actin 2).
30.4 0.79 Os05g0305600 Disease resistance protein family protein.
30.8 0.74 Os04g0438700 Similar to Muscleblind-like protein.
31.5 0.77 Os10g0420000 Conserved hypothetical protein.
31.5 0.77 Os01g0605600 Conserved hypothetical protein.
32.4 0.76 Os06g0611000 Similar to 65kD microtubule associated protein.
36.1 0.73 Os05g0169600 Serine/threonine protein kinase domain containing protein.
36.8 0.76 Os09g0281900 Thyroid hormone receptor-associated protein complex component TRAP170- like protein.
37.8 0.79 Os01g0115600 Similar to LRK14.
39.5 0.78 Os09g0357400 Disease resistance protein family protein.
41.0 0.70 Os01g0327600 Conserved hypothetical protein.
41.2 0.72 Os10g0381800 Conserved hypothetical protein.
41.9 0.77 Os11g0171800 Protein kinase-like domain containing protein.
44.0 0.77 Os08g0197000 Cyclin-like F-box domain containing protein.
45.1 0.72 Os04g0642000 Similar to MDR-like p-glycoprotein.
47.2 0.75 Os08g0159800 Zinc finger, CCCH-type domain containing protein.
48.9 0.64 Os05g0497100 Similar to Chromosome condensation protein.
52.0 0.74 Os03g0670200 Similar to YJR013Wp (Fragment).
52.3 0.72 Os06g0148600 Protein of unknown function DUF295 family protein.
53.7 0.77 Os02g0755500 Similar to UDP-glycosyltransferase 85A8.
54.5 0.75 Os03g0326300 Zinc finger, RING-type domain containing protein.
56.0 0.77 Os01g0678000 Conserved hypothetical protein.
57.0 0.73 Os08g0206900 UTP--glucose-1-phosphate uridylyltransferase family protein.
57.9 0.68 Os12g0141600 Peptidase, trypsin-like serine and cysteine domain containing protein.
59.1 0.75 Os01g0617700 Similar to CENP-C (Fragment).
60.0 0.76 Os09g0249700 Protein phosphatase 2A A subunit (Phosphatase 2A regulatory A subunit).
61.5 0.75 Os09g0313500 Disease resistance protein family protein.
61.7 0.68 Os08g0337100 Conserved hypothetical protein.
63.2 0.72 Os01g0193900 DIRP family protein.
64.7 0.72 Os11g0503400 Armadillo-like helical domain containing protein.
67.3 0.72 Os06g0704800 Transcriptional coactivation domain containing protein.
68.0 0.76 Os01g0543600 Cytochrome P450 family protein.
69.5 0.73 Os02g0168400 Hypothetical protein.
70.3 0.74 Os05g0363600 Conserved hypothetical protein.
72.4 0.72 Os01g0551900 WD40-like domain containing protein.
72.5 0.76 Os01g0178900 Hypothetical protein.
74.6 0.74 Os07g0647400 BSD domain containing protein.
75.3 0.75 Os01g0117300 Protein kinase-like domain containing protein.
78.2 0.74 Os04g0118500 Similar to Peptidyl-prolyl cis-trans isomerase 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1) (MdPin1).
79.1 0.71 Os05g0588700 Histone deacetylase interacting domain containing protein.
84.0 0.69 Os01g0904400 Similar to Chromosome assembly protein homolog.
84.2 0.63 Os08g0271400 Conserved hypothetical protein.
85.1 0.73 Os03g0321400 Protein of unknown function DUF1692 domain containing protein.
88.7 0.75 Os11g0226700 NB-ARC domain containing protein.
89.5 0.74 Os05g0479800 Disease resistance protein family protein.
91.0 0.75 Os01g0572300 Zinc finger, C2H2-type domain containing protein.
92.0 0.74 Os11g0470200 Protein kinase-like domain containing protein.
92.6 0.73 Os06g0195900 NOG, C-terminal domain containing protein.
92.8 0.69 Os03g0138100 RNA-binding region RNP-1 (RNA recognition motif) domain containing protein.
93.5 0.74 Os03g0130500 EPS15 homology (EH) domain containing protein.
93.5 0.70 Os12g0194100 Hypothetical protein.
94.7 0.75 Os09g0304800 Conserved hypothetical protein.
97.8 0.75 Os05g0546800 Conserved hypothetical protein.
98.2 0.73 Os02g0667000 Complex 1 LYR protein family protein.
98.4 0.72 Os08g0296700 Disease resistance protein family protein.
98.6 0.70 Os01g0633200 Similar to X1 (Fragment).
99.2 0.68 Os01g0516700 Glycosyl transferase, family 28 domain containing protein.
99.3 0.74 Os05g0463600 Conserved hypothetical protein.
99.4 0.67 Os03g0266200 Similar to Enolase (EC 4.2.1.11) (Fragment).
99.7 0.74 Os07g0273700 Transcriptional factor B3 family protein.
100.9 0.75 Os06g0688100 RNA polymerase I specific transcription initiation factor RRN3 family protein.
101.4 0.72 Os02g0593400 Conserved hypothetical protein.
101.8 0.71 Os03g0160200 Conserved hypothetical protein.
102.4 0.73 Os01g0780900 Conserved hypothetical protein.
103.1 0.50 Os02g0174900 Non-protein coding transcript, uncharacterized transcript.
103.5 0.74 Os10g0470700 Similar to Peptide transporter.
103.6 0.73 Os01g0920000 CBS domain containing protein.
103.7 0.73 Os01g0204000 Conserved hypothetical protein.
105.3 0.75 Os05g0549800 Transcriptional factor B3 family protein.
105.9 0.71 Os11g0235300 Non-protein coding transcript, unclassifiable transcript.
106.4 0.74 Os05g0289400 Similar to CRN (Crooked neck) protein.
106.5 0.72 Os08g0560600 Conserved hypothetical protein.
107.8 0.72 Os08g0104100 Conserved hypothetical protein.
108.4 0.71 Os11g0513500 Conserved hypothetical protein.
109.2 0.74 Os01g0117200 Similar to ARK protein (Fragment).
109.3 0.74 Os02g0504100 Conserved hypothetical protein.
109.6 0.74 Os07g0111400 WRKY transcription factor 29.
110.4 0.72 Os01g0300600 Borrelia outer surface lipoprotein family protein.
110.4 0.71 Os07g0657200 WD40-like domain containing protein.
111.4 0.73 Os07g0535200 Cyclin-like F-box domain containing protein.
111.7 0.73 Os02g0281900 Disease resistance protein family protein.
113.2 0.69 Os09g0566400 Protein of unknown function DUF1618 domain containing protein.
115.5 0.72 Os02g0822000 Conserved hypothetical protein.
115.9 0.71 Os03g0366800 Cyclin-like F-box domain containing protein.
116.7 0.73 Os05g0202800 Conserved hypothetical protein.
118.8 0.71 Os06g0638300
119.0 0.61 Os01g0162500 Leucine-rich repeat, typical subtype containing protein.
119.1 0.70 Os03g0733400 Zinc finger, BED-type predicted domain containing protein.
119.8 0.72 Os07g0180700 Similar to Major facilitator superfamily antiporter.
120.5 0.72 Os01g0668300 Conserved hypothetical protein.
123.4 0.71 Os02g0793100 Conserved hypothetical protein.
126.0 0.74 Os03g0158500 YT521-B-like protein family protein.
126.4 0.72 Os04g0254300 Conserved hypothetical protein.
127.9 0.72 Os09g0463700 Similar to AHM1.
131.0 0.71 Os08g0196200 Leucine-rich repeat 2 containing protein.
131.0 0.70 Os03g0694600 Conserved hypothetical protein.
131.2 0.73 Os08g0100400 RINGv domain containing protein.
131.2 0.73 Os03g0647600 Similar to Nf-Y-A subunit.
133.5 0.73 Os07g0554900 Cyclin-like F-box domain containing protein.
134.1 0.73 Os11g0676500 Similar to NBS-LRR type resistance protein (Fragment).
136.0 0.71 Os01g0748800 PEBP family protein.
138.5 0.71 Os06g0589300 Viral coat and capsid protein family protein.
138.6 0.70 Os02g0434800
139.0 0.69 Os01g0308300 Disease resistance protein family protein.
139.5 0.49 Os07g0688800 Aldehyde dehydrogenase domain containing protein.
140.9 0.71 Os01g0190400 Similar to Hexokinase.
144.1 0.73 Os01g0824800 Conserved hypothetical protein.
144.2 0.73 Os12g0170400 Zinc finger, C2H2-type domain containing protein.
144.8 0.71 Os12g0594600 SKP1 component family protein.
147.2 0.62 Os01g0511300 Proteasome component region PCI domain containing protein.
148.1 0.64 Os03g0594700 Conserved hypothetical protein.
148.8 0.71 Os07g0438300 Conserved hypothetical protein.
149.5 0.72 Os07g0635300 Similar to Cytochrome P450.
150.5 0.72 Os02g0227700 Protein kinase domain containing protein.
150.7 0.58 Os02g0831600 AGO1 homologous protein.
150.9 0.71 Os11g0513900 Conserved hypothetical protein.
152.3 0.72 Os11g0672200 Conserved hypothetical protein.
152.5 0.71 Os06g0687700 Similar to T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta) (HIV-1 Nef interacting protein).
153.1 0.73 Os04g0573900 Similar to Cytochrome P450-like protein.
155.8 0.69 Os08g0193600 Cyclin-like F-box domain containing protein.
155.9 0.66 Os01g0182200 Similar to Small basic membrane integral protein ZmSIP1-2.
156.7 0.72 Os01g0653800 WD40-like domain containing protein.
158.5 0.70 Os11g0173500 Protein kinase-like domain containing protein.
159.2 0.71 Os01g0977600 Armadillo-like helical domain containing protein.
160.8 0.72 Os12g0205500 Disease resistance protein family protein.
161.0 0.72 Os12g0635500 Protein of unknown function DUF266, plant family protein.
161.1 0.62 Os10g0508500 Similar to Tubulin folding cofactor D.
162.0 0.70 Os07g0258700 BTB domain containing protein.
162.1 0.70 Os02g0474700 Armadillo-like helical domain containing protein.
162.9 0.65 Os10g0122600 Cellular retinaldehyde binding/alpha-tocopherol transport family protein.
163.3 0.71 Os08g0558000 Similar to 60S ribosomal protein L10a-3.
163.9 0.72 Os03g0601000 Conserved hypothetical protein.
164.1 0.70 Os03g0711400 Similar to Coatomer alpha subunit.
164.2 0.65 Os10g0562500 Similar to Protein kinase KIPK.
164.9 0.72 Os04g0371000 Four-helical cytokine family protein.
165.4 0.72 Os02g0612200 Conserved hypothetical protein.
166.4 0.73 Os08g0101800 Protein of unknown function DUF821, CAP10-like family protein.
166.4 0.66 Os04g0470300 Protein of unknown function UPF0136, Transmembrane family protein.
166.8 0.72 Os05g0545900 Conserved hypothetical protein.
167.3 0.72 Os11g0225300 Disease resistance protein family protein.
168.0 0.68 Os08g0407600 Protein of unknown function DUF581 family protein.
168.6 0.71 Os03g0168800 Conserved hypothetical protein.
170.6 0.68 Os02g0133300 Similar to Structural maintenance of chromosome 3 (Fragment).
170.8 0.71 Os09g0471400 Protein kinase-like domain containing protein.
172.1 0.72 Os07g0130800 Similar to Resistance protein candidate (Fragment).
172.7 0.70 Os01g0682200 Similar to GPI transamidase component GAA1.
173.5 0.68 Os01g0549400 Similar to RNA helicase-like protein DB10.
174.7 0.68 Os09g0267500 WD-40 repeat containing protein.
176.6 0.62 Os02g0684500 Similar to Histone H4.
176.6 0.68 Os03g0417700 Similar to Cytochrome P-450.
178.5 0.71 Os05g0169400 Protein of unknown function DUF1421 family protein.
179.2 0.72 Os10g0531400 Conserved hypothetical protein.
181.5 0.61 Os05g0533700 Similar to NADH-ubiquinone oxidoreductase 20 kDa subunit, mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-20KD) (CI-20KD).
184.2 0.70 Os06g0674100 Conserved hypothetical protein.
184.2 0.72 Os07g0575600 Similar to Lectin-like receptor kinase 7;2.
185.5 0.70 Os11g0172300 Conserved hypothetical protein.
185.7 0.65 Os07g0458700 Conserved hypothetical protein.
188.1 0.66 Os02g0684600 Hypothetical protein.
190.0 0.72 Os05g0149600 Similar to Cullin-1.
190.1 0.72 Os01g0602200 Similar to Cytochrome P450 monooxygenase CYP72A5 (Fragment).
190.6 0.72 Os06g0328900 Cytochrome P450 family protein.
192.6 0.70 Os02g0173500 Similar to Cholinephosphate cytidylyltransferase.
192.8 0.71 Os06g0113500 Conserved hypothetical protein.
193.4 0.71 Os10g0466000 Conserved hypothetical protein.
193.7 0.70 Os05g0378900 Conserved hypothetical protein.
194.1 0.71 Os01g0253300 Importin alpha-1a subunit.
195.2 0.66 Os02g0732700 Conserved hypothetical protein.
196.2 0.71 Os09g0306700 Similar to Phytochrome and flowering time 1 protein.
198.6 0.70 Os07g0636100 Protein of unknown function DUF573 family protein.
199.1 0.69 Os02g0819200 Thioredoxin domain 2 containing protein.
199.6 0.68 Os06g0614100 Eukaryotic transcription factor, DNA-binding domain containing protein.
200.1 0.71 Os02g0688500 ALG6, ALG8 glycosyltransferase family protein.
200.4 0.68 Os12g0166000 Peptidase S59, nucleoporin family protein.
200.9 0.71 Os10g0124300 Similar to RGH1A.
203.5 0.69 Os02g0768000 Conserved hypothetical protein.
208.0 0.68 Os06g0206100 Similar to Gb protein.
208.2 0.70 Os03g0728900 Basic helix-loop-helix dimerisation region bHLH domain containing protein.
208.3 0.71 Os10g0469100 Conserved hypothetical protein.
209.8 0.59 Os01g0391100 Similar to ATP-binding cassette, sub-family F, member 2 (Iron inhibited ABC transporter 2) (HUSSY-18).
210.8 0.70 Os06g0142500 Calycin-like family protein.
211.3 0.69 Os07g0273600 Hypothetical protein.
211.6 0.65 Os04g0274400 YL1 nuclear, C-terminal domain containing protein.
212.4 0.68 Os01g0233900 Ubiquitin-conjugating enzyme, E2 domain containing protein.
213.4 0.69 Os01g0754200 Glycosyl transferase, family 48 protein.
214.2 0.66 Os08g0143500 Glycosyl transferase, family 14 protein.
217.2 0.69 Os07g0131100 Legume lectin, beta domain containing protein.
217.5 0.66 Os06g0677600 Like-Sm ribonucleoprotein, core family protein.
218.5 0.68 Os09g0127800 Similar to Coatomer alpha subunit.
218.8 0.70 Os11g0703900 Heat shock protein 70.
220.4 0.66 Os01g0805100 Conserved hypothetical protein.
220.6 0.69 Os10g0498700 WD40-like domain containing protein.
221.4 0.67 Os02g0714500 Tetratricopeptide-like helical domain containing protein.
222.6 0.68 Os01g0214300 Conserved hypothetical protein.
223.4 0.67 Os05g0467600 Conserved hypothetical protein.
225.4 0.68 Os05g0144300 DEAD/DEAH box helicase, N-terminal domain containing protein.
225.5 0.70 Os04g0581000 Similar to Flavanone 3-hydroxylase-like protein.
226.5 0.66 Os05g0486600
227.9 0.69 Os07g0122000 Protein of unknown function DUF1719, Oryza sativa family protein.
228.1 0.66 Os05g0463400 PWWP domain containing protein.
229.9 0.67 Os04g0476500 S15/NS1, RNA-binding domain containing protein.
230.0 0.66 Os03g0201000 Conserved hypothetical protein.
230.6 0.71 Os08g0548200 Similar to ER lumen protein retaining receptor-like protein.
231.1 0.66 Os02g0200900 Leucine-rich repeat, cysteine-containing containing protein.
231.4 0.64 Os05g0365700 Glycoside hydrolase, family 1 protein.
231.4 0.66 Os02g0570700 Cytochrome P450 family protein.
231.5 0.66 Os03g0661800 Peptidase, trypsin-like serine and cysteine domain containing protein.
232.6 0.71 Os07g0471300 Similar to Argonaute 4 protein.
232.7 0.69 Os07g0158900 Cyclin-like F-box domain containing protein.
235.1 0.68 Os01g0186600 Conserved hypothetical protein.
236.0 0.68 Os07g0655400 Conserved hypothetical protein.
236.8 0.69 Os05g0160600 Peptidase, trypsin-like serine and cysteine domain containing protein.
240.5 0.64 Os11g0213700 Leucine-rich repeat, typical subtype containing protein.
241.8 0.59 Os12g0134200 Armadillo-like helical domain containing protein.
241.9 0.64 Os05g0358200 DNA primase, small subunit family protein.
242.9 0.68 Os06g0644100 Carboxypeptidase regulatory region domain containing protein.
243.2 0.70 Os02g0228300 Protein kinase-like domain containing protein.
243.6 0.60 Os01g0728900 Non-protein coding transcript, uncharacterized transcript.
243.8 0.60 Os04g0563300 Cyclin-like F-box domain containing protein.
245.0 0.65 Os10g0575200 Similar to Rme-8 homologue (Fragment).
245.0 0.69 Os04g0502200 Conserved hypothetical protein.
245.2 0.66 Os01g0824700 Cyclin-like F-box domain containing protein.
246.4 0.69 Os11g0223400 Conserved hypothetical protein.
246.9 0.67 Os07g0575700 Similar to Lectin-like receptor kinase 7;2.
247.2 0.70 Os11g0691500 EGF domain containing protein.
247.7 0.69 Os08g0233400 Ankyrin repeat containing protein.
248.8 0.59 Os03g0622500 Hypothetical protein.
249.4 0.66 Os11g0550100 Conserved hypothetical protein.
249.4 0.63 Os03g0135400 Cyclin-like F-box domain containing protein.
249.6 0.69 Os05g0278500 Transferase family protein.
250.1 0.65 Os02g0639700 UBA-like domain containing protein.
250.7 0.68 Os01g0542700 Eukaryotic transcription factor, DNA-binding domain containing protein.
252.9 0.66 Os07g0508000 Similar to ADR224Wp.
254.3 0.70 Os04g0636000 SPla/RYanodine receptor SPRY domain containing protein.
254.7 0.68 Os08g0383700 Repressor protein.
254.7 0.58 Os03g0698200 Conserved hypothetical protein.
255.7 0.69 Os07g0447000 Protein of unknown function DUF594 family protein.
255.7 0.59 Os11g0640700 Conserved hypothetical protein.
256.0 0.66 Os03g0589300 Ovarian tumour, otubain domain containing protein.
256.6 0.66 Os01g0182100 Protein of unknown function DUF1618 domain containing protein.
257.0 0.65 Os01g0182700 Similar to WRKY transcription factor 34.
257.6 0.59 Os03g0405500 Similar to PDI-like protein.
258.0 0.64 Os09g0516200 Transcription factor RF2a. Splice isoform 2.
259.0 0.69 Os02g0134300 Protein of unknown function DUF701, zinc-binding putative family protein.
260.1 0.66 Os02g0827300 Protein of unknown function DUF382 domain containing protein.
260.3 0.55 Os12g0621900 Conserved hypothetical protein.
261.4 0.65 Os03g0112400 AP2 clathrin adaptor, alpha and beta chain, appendage domain containing protein.
261.9 0.68 Os01g0975300 Similar to Typical P-type R2R3 Myb protein (Fragment).
263.7 0.64 Os01g0858500 Similar to Transcription initiation factor TFIID subunit 12 (Transcription initiation factor TFIID 20/15 kDa subunits) (TAFII-20/TAFII-15) (TAFII20/TAFII15).
265.9 0.64 Os01g0500500
266.9 0.68 Os06g0731100 Conserved hypothetical protein.
266.9 0.66 Os01g0153100 Similar to Histone H2B-3 (Fragment).
267.9 0.67 Os04g0680400 Similar to Allantoinase (EC 3.5.2.5).
270.4 0.67 Os06g0624200 Non-protein coding transcript, putative npRNA.
271.5 0.69 Os09g0467200 Similar to Glutathione S-transferase GST 23 (EC 2.5.1.18) (Fragment).
271.6 0.68 Os01g0557400 Cyclin-like F-box domain containing protein.
271.9 0.65 Os05g0143400 GINS complex, Sld5 component family protein.
272.6 0.59 Os12g0124100 Similar to Disease resistance gene analog PIC13 (Fragment).
272.8 0.67 Os06g0622300 AT-rich interaction region domain containing protein.
274.8 0.65 Os02g0741400 Conserved hypothetical protein.
278.4 0.69 Os10g0445900 Hypothetical protein.
278.4 0.68 Os09g0361700 Protein of unknown function UPF0203 family protein.
280.1 0.64 Os01g0549500 Phox-like domain containing protein.
280.1 0.65 Os02g0114000 Bromodomain containing protein.
282.4 0.60 Os11g0536800 Amidase family protein.
282.5 0.63 Os06g0644300 Disease resistance protein family protein.
282.6 0.69 Os02g0595400 Conserved hypothetical protein.
283.9 0.69 Os09g0371200 Major facilitator superfamily MFS_1 protein.
284.0 0.59 Os01g0828300 Protein of unknown function DUF248, methyltransferase putative family protein.
284.4 0.66 Os03g0737900 Conserved hypothetical protein.
285.4 0.41 Os02g0169400 Similar to Argonaute 4 protein.
285.4 0.67 Os06g0673500 Similar to Ubiquitin.
286.3 0.68 Os07g0271000 Similar to GDP dissociation inhibitor protein OsGDI1.
287.1 0.68 Os01g0117500 Similar to LRK14.
287.4 0.67 Os11g0649300 Hypothetical protein.
289.0 0.67 Os04g0107500 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region domain containing protein.
291.0 0.63 Os02g0573200 Similar to Cryptochrome 1.
291.3 0.68 Os01g0115700 Protein kinase-like domain containing protein.
292.0 0.66 Os12g0438300 Disease resistance protein family protein.
293.1 0.68 Os05g0318600 Similar to Protein kinase (Pto kinase) (Serine/threonine protein kinase Pto).
293.4 0.64 Os09g0408000 Tetratricopeptide-like helical domain containing protein.
295.0 0.67 Os01g0220400 Conserved hypothetical protein.
295.4 0.67 Os01g0125800 Nitrous oxide reductase, N-terminal domain containing protein.
298.4 0.60 Os02g0132500 Similar to Common plant regulatory factor 7.
299.2 0.68 Os05g0583100 HAT dimerisation domain containing protein.
300.2 0.69 Os05g0418000 GDP dissociation inhibitor protein OsGDI1.
303.3 0.58 Os02g0180500 Similar to Chorismate mutase CM2 (EC 5.4.99.5) (Chorimate mutase).
303.8 0.65 Os11g0104900 Clathrin heavy chain, linker domain containing protein.